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Immokalee is a census-designated place (CDP) in Collier County, Florida, United States. The population was 19,763 at the 2000 census. It is part of the Naples–Marco Island Metropolitan Statistical Area. The settlement was originally known as Gopher Ridge. The etymology of the name appears to mean either "My Home" or "His Home".

Farms around Immokalee produce tomatoes that are well-regarded across South Florida.

The Immokalee Seminole Reservation and casino is located there. The Audubon Society's Corkscrew Swamp Sanctuary is nearby.